HPLC Fingerprinting in Bioinformatics & Computational Biology
Fingerprinting is a quality control model that builds upon spectroscopic and chromatographic technology. It is different from the traditional quality control model in the sense that fingerprinting looks at the “complete information” or comprehensiveness of the chromatograph, and displays integrated quality information. Comprehensiveness and fuzziness are the two basic traits of a fingerprint. The similarity of fingerprints is established through these basic traits. Fingerprint analysis focuses on accurate identification (of similar peaks), and not on precise calculation. The comparison of fingerprints emphasizes similarity and the fingerprints compared do not need to be exactly the same.
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