Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 6th International Conference and Exhibition on Advances in Chromatography & HPLC Techniques Barcelona, Spain.

Day 1 :

Keynote Forum

Haifei Zhang

University of Liverpool, UK

Keynote: The development of spheres-on-sphere silica particles for fast and efficient HPLC separation

Time : 10:00-10:35

OMICS International Chromatography-HPLC Congress 2018 International Conference Keynote Speaker Haifei Zhang photo
Biography:

Haifei Zhang is a Senior Lecturer in the Department of Chemistry at University of Liverpool. He has completed his undergraduate and Master degrees in Chemical Engineering and PhD in Physical Chemistry from Chinese Academy of Science. He has published 90 peer reviewed research papers with h-index of 29 and filed 9 international patents as a Co-inventor. He won the 12th Desty Memorial Award in 2007 for his innovative work in the manufacture of porous materials and their possible application in chromatography. He has also written five book chapters and one book (to be published by Wiley in 2018). His main research interests are on porous materials, colloids, carbon materials, and nanostructured materials for separation and energy storage applications.

Abstract:

Core-shell silica particles have been developed and employed by various manufacturers for fast and efficient HPLC separations with relatively low back pressure. However, core-shell silica particles are usually fabricated by the time-consuming layer-by-layer technique and usually followed by a lengthy classification process to obtain uniform particles. Recently, we have developed a one-pot synthesis method at room temperature to produce the unique spheres-on-sphere (SOS) silica particles. These SOS particles are comprised of silica nanospheres attached to silica microspheres. The size and number of silica nanospheres are tunable. The interstices between the surface silica nanospheres on the solid microspheres generate the macroporosity for fast and efficient HPLC separations with low back pressure, particularly for large bio-macromolecules. Importantly, these SOS particles are very uniform directly from synthesis (hence classification in unnecessary) and mesoporosity and additional functional particles may be introduced so that these particles can be efficiently used for fast separation of a wide range of analytes, including peptides, proteins, small molecules, and isomers. This talk will cover the preparation and characterization of SOS particles and their various applications in HPLC.

 

Keynote Forum

Sergio Guazzotti

Thermo Fisher Scientific, USA

Keynote: Ion chromatography solution for applied pharmaceutical markets

Time : 10:35-11:10

OMICS International Chromatography-HPLC Congress 2018 International Conference Keynote Speaker Sergio Guazzotti photo
Biography:

Sergio Guazzotti is a Senior Global Marketing Director for ion chromatography and sample preparation at Thermo Fisher Scientific. Prior to this role, he was the Global Marketing Director for gas chromatography/gas chromatography-mass spectrometry also at Thermo Fisher Scientific. He joined the company in 2008 as Senior Global Strategic Marketing Manager for HPLC and was later appointed as Senior Integration Manager to assist the integration of Dionex Corporation into Thermo Fisher Scientific. Prior to joining Thermo Fisher Scientific, he was the Vice President of Engineering and Technical Services at Nanostream, Inc. Earlier in his career, he was a Professor of Analytical Chemistry at the University of California, San Diego. He holds a PhD degree in Chemistry from the University of California.

Abstract:

An accurate understanding of the contents of any pharmaceutical entity helps to ensure both drug efficacy and patient’s safety. Over several decades, there has been significant improvement in the analytical methods and techniques ensuring critical quality attribute analysis of the pharmaceutical products. The solutions offered by Dionex Ion Chromatography systems are widely adopted and are everyday gaining more traction because of the several technological advancements and benefits in these Dionex IC systems. These advancements include superior accuracy, high-throughput, improved reliability, and environmental safety concerns which significantly contribute towards the critical analysis of the drug entity of interest. IC primarily relies on suppressed as well as non-suppressed conductivity detections for ionic species in pharmaceutical samples. Dionex IC systems can accurately analyze multiple anions/cations in a single injection, thereby, accelerating the analysis throughput. The productivity can be further improved by converting the single channel system to a dual-channel system where two different samples can be concurrently analyzed. Most recent advancement, Consumables Device Monitor, can automatically identify and tracks the installation time, use, and performance metrics of all the installed IC consumables. This feature can reduce any associated downtime due to consumable installation errors and can even schedule preventive maintenances. Such smart capabilities can significantly improve the productivity as well as lessen the burden on the analysts’ time in a fast-paced pharmaceutical laboratory.  All modern IC systems can make eluents automatically, allowing the consistent and reliable production of high purity IC eluent concentrations. The only routine reagent then needed is high-purity water. Consequently, the instrument pump seals and pistons only come into contact with deionized water instead of acids and bases which can precipitate. This extends the lifetime of pump seals and pistons, and significantly reduces the overall pump maintenance requirements. Dionex IC systems are constantly evolving with the changing times and needs. Recent IC systems are equipped with a tablet supporting 11 different languages with an intuitive interface. This tablet control enables direct local control of the system and its status. All these enhanced capabilities and advancements have only led to the successful adoption of IC for analyzing ionic species in pharmaceutical applications.