Chromatography Conferences 2019 | HPLC Conferences 2019 | Pharmaceutical Chemistry Conferences | Meetings | Events | 2019

Theme: Exploring the Scientific and Industrial Advancements in Chromatography Techniques

Advanced Chromatography 2019

Scientific Program

Renowned Speakers

DuÅ¡an Berek
Polymer Institute - SAS
Slovakia

Imre MolnÃ¡r
MolnÃ¡r-Institute for Applied Chromatography
Germany

MiloÅ¡ NetopilÃk
Institute of Macromolecular Chemistry AS CR,
Czech Republic

Cenk Andac
Istinye University
Turkey

Hans-JÃ¼rgen Rieger
MolnÃ¡r-Institute for Applied Chromatography
Germany

Dennis Fiorini
University of Camerino
Italy

Deborah Pacetti
University Politecnica delle Marche P.zza Rome
Italy

Zeynep Altintas
Technical University of Berlin
Germany

Sena Caglar
Istanbul University
Turkey

Joscha Breibeck
University of Vienna
Austria

Ana Casas
Ludwig-Maximilians-University
Germany

Feng Zhang
Shanghai Changzheng Hospital
China

Martina Hermannova
Contipro
Czech Republic

Tserendorj Tugsuu
National University of Mongolia, Mongolia
mongolia

Shao-Ting Wang
Renmin Hospital of Wuhan University
China

Dagmar Heinova
University of Veterinary Medicine in Kosice
Slovakia

Ahmad Ifseisi
King Saud University
Saudi Arabia

Michael Soll
Frontier Laboratories
Germany

Haifei Zhang
University of Liverpool
UK

Sergio Guazzotti
Thermo Fisher Scientific
USA

Mladen Krajacic
University of Zagreb
Croatia

Fotios Tsopelas
National Technical University of Athens
Greece

Monika Å ulekovÃ¡
University of Veterinary Medicine and Pharmacy in KoÅ¡ice
Slovakia

Clydewyn M Anthony
United States Pharmacopeial Convention
USA

Yuichi Negishi
Tokyo University of Science
Japan

Madhuri Singhal
Government M V M College
India

Mariana G Selener
University of Buenos Aires
Argentina

Amal Al Sabahi
Sultan Qaboos University
Oman

Sayaka Hashimoto
Tokyo University of Science
Japan

Kana Yoshida
Tokyo University of Science
Japan

Tamara Alvarez-Segura
University of Valencia
Spain

Susana Jesus
National Institute of Health Doutor Ricardo Jorge
Portugal

Lucia VÃ¡hovskÃ¡
University of Veterinary Medicine and Pharmacy
Slovakia

James A Oâ€™Hanlon
The University of Manchester
UK

Karen Gaudin
University of Bordeaux
France

Sergey Piletsky
University of Leicester
UK

Eduard Rogatsky
Wadsworth Center
USA

Evelien Wynendaele
Ghent University
Belgium

Michael John
Institute of Anorganische Chemie
Germany

Jennifer E Claus
Millipore Sigma
USA

D.S. Shokry
University of Huddersfield
UK

Tony Q Yan
Pfizer Inc
USA

Sergey N Krylov
York University
Canada

Britta Eggenreich
Vienna University of Technology
Austria

Rafea M Naffa
Massey University
New Zealand

Ramesh C Pandey
GDP Ayurvedic University
USA

Katsuhiro Maeda
Kanazawa University
Japan

Wojciech Strzalka
Jagiellonian University
Poland

Siu-Po IP
The Chinese University of Hong Kong
Hong Kong

Romain Kapel
University of Lorraine
France

Dong Wang
China Agricultural University
China

Fabian Holenstein
Novartis Institutes for Biomedical Research
Switzerland

Vignesh Rajamanickam
Vienna University of Technology
Austria

Berkant Kayan
Aksaray University
Turkey

Yun Fa
Chinese Academy of Sciences
China

Koray Sarkaya
DÃ¼zce University
Turkey

BogusÅ‚aw Buszewski
Nicolaus Copernicus University
Poland

Sheng Tang
Wuhan Institute of Technology
China

Canan Onac
Pamukkale University
Turkey

Hudson Polonini
Federal University of Juiz de Fora
Brazil

Nguyen Khanh Hoang
Industrial University of HoChiMinh City
Vietnam

Jorge Costa Pereira
University of Coimbra
Portugal

Ahmed Mohamed Ali Hemdan
Ahram Canadian University
Egypt

Maw-Rong Lee
National Chung Hsing University
Taiwan

Rudolf Kapeller
Austrian Agency for Health and Food Safety
Austria

Katarzyna Adamska
Poznan University of Technology
Poland

Mirtes Midori Tanae
Universidade Federal de SÃ£o Paulo
Brazil

Joseph J Pesek
San Jose State University
USA

PaweÅ‚ K Zarzycki
Koszalin University of Technology
Poland

Sena Yaman
Izmir Institute of Technology
Turkey

Aschwin van der Horst
Nuplex
Netherlands

Filip Cuyckens
Janssen R&D
Belgium

Jacob de Boer
VU University
Netherlands

Gaelle Coussot
UniversitÃ© de Montpellier
France

Allan Philippe
Koblenz-Landau University
Germany

Aleksandra Zatirakha
Lomonosov Moscow State University
Russia

Arieh Moussaieff
Hebrew University
Israel

Lanling Chu
Southeast University
China

Kal Karim
Leicester University
UK

Ludivine Ferey
University of Bordeaux
France

Anna Poliwoda
Opole University
Poland

Vladimir Gruznov
Trophimuk Institute of petroleum geology and geophysics
Russia

Hiroki Kuwano
Tohoku University
Japan

Oleg Shpigun
Lomonosov Moscow State University
Russia

Advanced Chromatography 2019

Advanced Chromatography 2019 organizing committee invites analytical expertise, researchers, professors, scientific communities, delegates, students, business professionals and executives to attend the “International Conference & Expo on Chromatography Techniques” which is to be held during April 22-24, 2019 Dublin, Ireland.

In the light of this theme, the conferenceseries aims to provide a forum for international researchers from various areas of analytical chemistry, pharmacy, pharmacology, bioinformatics and other life science groups by providing a platform for critical analysis of new data, and to share latest cutting-edge research findings and results about all aspects regarding advances in HPLC and Chromatography techniques.

The conference provides a platform to detail the research works of analytical expertise from various scientific backgrounds and the same can be perceived by young researchers and students. The conference mainly aims to promulgate knowledge on chromatography and unveil the advances in HPLC techniques. Both Life Sciences and Chemical Sciences need analytical techniques in course of research work and therefore Advanced Chromatography 2019 would be a perfect venue to share and develop knowledge on key analytical tools.

Target Audience:

Analytical experts in chromatography
Research Heads from Research Centres
Leads from Pharmacy and Chemical Industries
Industrial expertise working with various novel solid & liquid columns
Marketing teams of Industries with novel products to show case at the conference
Directors and Professors from Universities and Institutions
Post-doctoral & PhD students working on analytical & Bio-analytical method development
Theoretical scientists working on deriving analytical hypotheses
Relevant Graduate and Post graduate students

The global life science and chemical instrumentation market is expected to reach $48.84 billion by 2020, at CAGR of 6.9%. Technological advancements in the analytical instruments, rising government spending on pharmaceutical R&D in emerging nations, increasing public and private life science research and development expenditure, growing food safety concerns, and progressing drug discovery and clinical diagnostics field are the key factors driving the growth of life science and chemical instrumentation market. Furthermore, growing proteomics market, rising environmental safety concerns, and increasing demand of analytical instruments from applied markets are some of the key factors offering new growth opportunities for the market players. The Europe Liquid Chromatography Reagents market is estimated to grow at a CAGR of 9.9% from 2014 to 2019. The market growth is fuelled by extensive use of chromatographic techniques in every minute analysis.

Conferenceseries organizes 1000+ Global events every year across the globe with support from 1000+ more scientific societies and Publishes 500 Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

With great keenness, we look forward to seeing you at Advanced Chromatography 2019

Track 1:- Major Chromatographic Techniques

Chromatography basically is a method of separation of compounds from a mixture. The technique is both analytical and preparative and is employed widely in industries as well as in laboratories. Chemical analysis is mostly done all over the world with chromatography or any other various techniques related to chromatography. Chromatography is a physical technique and has a vast application in chemical field starting from basic analytical chemistry to forensic science.

Some major chromatography techniques are:

Column chromatography is a method used to purify individual chemical compounds from mixtures of compounds. It is has preparative applications on scales ranging from small scale to large scale production. Relatively low cost and disposability of the stationary phase are the main advantages of column chromatography.

Paper chromatography involves placing a small dot or line of sample solution onto a strip of polar cellulose chromatography paper. The paper is placed in a glass chamber with a shallow layer of solvent and is sealed. As the solvent moves through the paper, it comes in contact with the sample mixture, which starts to rise up the paper with the solvent.

Thin layer chromatography (TLC) is a mostly used technique which involves a stationary phase of a thin layer of adsorbent like alumina, silica gel, or cellulose on a flat, inert layer of substrate. Advantages of TLC are better separations, faster runs, and the choice of different adsorbents. Better quantification and resolution can be achieved with high-performance TLC.

Displacement chromatography is a preparative technique in which a sample is placed onto the head of the column and is then displaced by a solute that is more strongly adsorbed than the components of the original mixture. As a result the components are resolved into consecutive rectangular zones of highly concentrated pure substances rather than solvent-separated peaks.

Gas chromatography (GC) is commonly used in analytical chemistry for separating and analysing compounds that can be vaporized without decomposition. In this process, the mobile phase (or "moving phase") is a carrier gas; commonly an inert gas such as helium or an unreactive gas such as nitrogen is generally used. Stationary phase is a microscopic layer of liquid or polymer on an inert solid support, within a glass or metal tubing.

Supercritical fluid chromatography (SFC) –in this technique the mobile phase is a fluid above and relatively close to its critical temperature and pressure. SFC mainly utilizes carbon dioxide as the mobile phase; in order to pressurize the chromatographic flow. Supercritical phase represents a state in which liquid and gas properties combine.

Expanded Bed Adsorption (EBA) Chromatographic Separation is used for target protein from a raw feed stream when it passes through a chromatography column system containing adsorbent beads. Using this technique the unprocessed raw compound can be treated directly in the chromatographic column, avoiding clarification and pre-treatment steps.

19^th World Congress on Pharmaceutical Sciences and Innovations in Pharma Industry February 25-27, 2019 Berlin, Germany; 7^th Edition of International Conference on Pharmacognosy and Medicinal Plants March 11-12, 2019 London, UK; 20^th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 18-20, 2019 Edinburgh, Scotland; 10^th Global Organic & Inorganic Chemistry Conference 2019 March 21-22, 2019 Rome, Italy; 12^th European Biosimilars Congress April 15-16, 2019 Berlin, Germany; 7^th International Conference and Exhibition on Materials Science and Chemistry May 20-22, 2019 Zurich, Switzerland; 21^st Annual European Pharma Congress May 20-21, 2019 Zurich, Switzerland; 5^th International Conference on Electrochemistry May 27-28, 2019 Barcelona, Spain

Related Societies:

Europe: German Chemical Society; Italian Society for Separation Science; British Mass Spectrometry Society; Royal Netherlands Chemical Society; Swedish Mass Spectrometry Society; Swedish Chemical Society; Chromatography and Electrophoresis Group of the Czech Chemical Society; Separation Sciences Foundation of Denmark; Association Francophone des Sciences Separatives; Hungarian Society for Separation Science.

Asia: Korean American Chromatography Association; Australian and New Zealand Society for Mass Spectrometry; Federation of Asian Chemical Societies; Royal Australian Chemical Institute; Hong Kong Society of Mass Spectrometry, The Japan Society for Analytical Chemistry; Israel Society for Analytical Chemistry; Chromatographic Society of India

USA: Federation of Analytical Chemistry and Spectroscopy Societies; Chinese American Chromatography Association; Association of Analytical Communities; Society for Electro analytical Chemistry; Canadian Society for Chemistry; Canadian Society for Mass Spectrometry; Society for Analytical Chemists of Pittsburgh; California Separation Science Society; Society for Applied Spectroscopy; International Society of Chemical Ecology.

Track 2:- Advances in Chromatography Instrumentations

HPLC is a popular method of analysis for natural products because of its high accuracy, precision and is not differed by the stability or the volatility of the compounds. HPLC combined with diode array detector (HPLC-DAD), mass spectrometer (HPLC-MS) have been successfully utilized for the qualitative and quantitative determination of various types of phyto-constituents like alkaloids, glycosides, tannins, tri-terpenes, flavonoids etc. HPLC methods are used readily for the determination of drug in biological fluids and pharmaceutical dosage forms. HPLC determination with spectroscopic detection is useful for routine quality control of drugs in pharmaceutical dosage forms and stability studies.

A chromatographic detector is capable of establishing both the identity and concentration of eluting components in the mobile phase stream. A broad range of detectors are available to meet different sample requirements. Detectors respond to a particular compound only and the response is independent of mobile phase composition and the response of bulk property detectors is dependent on collective changes in composition of sample and mobile phase. Specific detectors are UV-VIS, Photo diode array, fluorescence, and mass spectroscopic detectors. Bulk Property detectors include refractive index, electrochemical and light scattering detectors.

6^th World Congress and Exhibition on Antibiotics and Antibiotic Resistance June 03-04, 2019 London, UK; 22^nd International Conference and Exhibition on Pharmaceutical Formulations June 03-04, 2019 London, UK; 11^th World Congress on Medicinal Chemistry and Drug Design June 10-11, 2019 Edinburgh, Scotland; 8^th World Congress on Mass Spectrometry June 10-11, 2019 Edinburgh | Scotland; 6^th International Conference and Exhibition on Natural Products Chemistry and Medicinal Plants Research June 24-25, 2019 Vienna, Austria; 24^th World Congress on Pharmacology August 19-20, 2019 Vienna, Austria; 23^rd International Conference and Exhibition on Pharmacovigilance & Drug Safety July 18-19, 2019 Rome, Italy

Related Societies:

Track 3:- Chromatography-Mass Spectroscopy Analysis

Liquid chromatography is a fundamental separation technique in the life sciences and related fields of chemistry. Unlike gas chromatography, which is unsuitable for non-volatile and thermally fragile molecules, liquid chromatography can safely separate a very wide range of organic compounds, from small-molecule drug metabolites to peptides and proteins. Traditional detectors for liquid chromatography include refractive index, electrochemical, fluorescence, and ultraviolet-visible (UV-Vis) detectors. Some of these generate two-dimensional data; that is, data representing signal strength as a function of time. Others, including fluorescence and diode array UV-Vis detectors, generate three dimensional data. Three-dimensional data include not only signal strength but spectral data for each point in time.

Mass spectrometers also generate three-dimensional data. In addition to signal strength, they generate mass spectral data that can provide valuable information about the molecular weight, structure, identity, quantity, and purity of a sample. Mass spectral data add specificity that increases confidence in the results of both qualitative and quantitative analyses.

Related Societies:

Track 4:- Chromatography in Pharmacy & Pharmaceutical

One of the most characteristic features of the development in the methodology of pharmaceutical and biomedical analysis is that HPLC became undoubtedly the most important analytical method for identification and quantification of drugs, either in their active pharmaceutical ingredient or in their formulations during the process of their discovery, development and manufacturing.

Drug development starts with the discovery of a molecule with a therapeutic value. This can be done by high throughput screening during which separations by fast or ultra-fast HPLC are performed. At the discovery stage there can be also characterizing synthetic or natural products. Drug metabolism and pharmacokinetics (DMPK) is the step where the candidate compounds for drug are tested for their metabolism and pharmacokinetics. The studies involve use of LC-MS or LC-MS/MS. The goal in the discovery stage of drug development is to discover a new, safe and active chemical entity (NCE) that will become medication for diseases. During the last decade parallel synthesis of potential lead compounds, using combinatorial chemistry has been done. Due to its high sensitivity and selectivity, HPLC coupled with tandem mass spectrometry, HPLC-MS/MS has become the predominant method in bioassays, and pharmacokinetic and metabolic studies.

Chromatography and spectroscopy are orthogonal techniques, i.e. their types of information are very different and are specific. Chromatography is a separation method and spectroscopy is a technique which yields a ‘fingerprint’ of individual or from mixture of molecules. HPLC is a technique for separation, quantification and identification of components in a mixture. It is especially suitable for compounds which are not easily volatilized, thermally unstable and have high molecular weights. The advantage of UV method over HPLC method is that the UV method does not require the elaborate treatment and procedures usually associated with chromatographic method. It is less time consuming and economical. The HPLC and UV spectrometry methods are adequate methods to quantify a drug in pure form and its dosage form. Since these methods are simple, specific, rapid, precise and accurate, they may be successfully and conveniently adopted for routine quality control analysis of drugs in bulk and pharmaceutical dosage form.

Related Societies:

Track 5:- Chromatography in Food Science Technology

With modern technology and facilities, our food supply is more diverse and more highly processed than ever before. To ensure the safety and nutritional quality of our food many countries and organization have promulgated regulations that stipulate acceptable levels for individual chemical additives, residues and contaminants in food products. Other regulations require food packaging to list ingredients relating to nutritional content, such as preservative, artificial chemicals, unsaturated and saturated fat. Food manufacturers and processors themselves must be able to assess product quality. Meeting all of these requirements is the function of food analysis.

Increasingly, food analysis methods are built around high-performance liquid chromatography (HPLC), which has proven to be an optimal technology for detecting and/or quantifying the vast majority of food analytes. These methods employ a stepwise approach while separating and analysis the sample, it first removes the sample matrix, then isolates the analytes of interest and individually resolves them on a chromatographic column. The efficiency of the separation depends on, among other things, the differential interaction of analytes of interest with both mobile and column stationary phases during the separation. It is important to classify food analytes according to their relative volatility and polarity are factors that must be considered when selecting an appropriate analytical method for their determination.

Gas chromatography (GC) is widely used in applications involving food analysis. High-performance liquid chromatography (HPLC) and to mention state-of-the-art GC techniques used in the major applications pertaining to the quantitative and/or qualitative analysis of food composition, natural products, food additives, flavour and aroma components, a variety of transformation products, and contaminants, such as environmental pollutants, pesticides, fumigants, natural toxins, veterinary drugs, and packaging materials. Among the several new qualitative and quantitative techniques being developed in food analysis applications, fast-GC/mass spectrometry (MS) will have the most impact in the next decade. Three approaches to fast-GC/MS include low-pressure GC/MS, GC/time-of-flight (TOF)-MS and GC/supersonic molecular beam (SMB)-MS.

Related Societies:

Track 6:- Biochemical Applications of Chromatography

HPLC is a very common method for metabolomics analysis. With the invention of electrospray ionization, HPLC is coupled to mass spectroscopy. HPLC has lower chromatographic resolution, requires no derivation for polar molecules and separates molecules in the liquid phase. HPLC has the advantage of much wider range of analytes measurements with a higher sensitivity than gas chromatographic methods. Relevant to proteomics, due to the complex structure and nature of proteins, instrumentation and methods development for sample clean-up, pre-concentration, fractionation, chromatographic separation and detection becomes an immediate requirement for the identification of peptides and proteins. Latest techniques and equipment for separation and detection include nano-HPLC and multidimensional HPLC for protein and peptide separation. HPLC is considered as most reliable and most sensitive technique in genomics used to determine DNA methylation. The nucleosides and nucleotides of DNA are separated and quantified by HPLC-UV method. HPLC finds applications in glycomics and lipidomics where glycan part is cleaved either enzymatically or chemically from the target and subjected to analysis. HPLC has a wide application in lipidomics to separate lipids prior to mass spectrometry. Separation can be achieved by either reverse-phase (RP) HPLC or normal-phase (NP) HPLC.

Related Societies:

Track 7:- HPLC Fingerprinting in Bioinformatics & Computational Biology

HPLC techniques are applied for purification and separation of various biological samples. The analysed samples are subjected to sequencing studies either manually or using different software’s. This is studied as Data mining and sequence analysis. HPLC is also used for characterization of various metabolites.

Fingerprinting is a quality control model that builds upon spectroscopic and chromatographic technology. It is different from the traditional quality control model in the sense that fingerprinting looks at the “complete information” or comprehensiveness of the chromatograph, and displays integrated quality information. Since the secondary metabolites, which are chemical components of medicinal herbs, are inherently unstable, the fingerprints of these chemicals possess a fuzziness that cannot be precisely measured, just like the fuzzy phenomenon in our daily lives. Comprehensiveness and fuzziness are the two basic traits of a fingerprint. The similarity of fingerprints is established through these basic traits. Fingerprint analysis focuses on accurate identification (of similar peaks), and not on precise calculation. The comparison of fingerprints emphasizes similarity and the fingerprints compared do not need to be exactly the same. When it is impossible to find out all the complex components of a traditional medicine, fingerprints can be used to check the stability of the intrinsic quality of the medicine.

Related Societies:

Track 8:- Analytical & Bio-analytical Applications of Chromatography

HPLC can be used in both qualitative and quantitative applications that are for both compound quantification and identification. Normal phase HPLC is rarely used now, almost all HPLC separation can be performed in reverse phase. Reverse phase HPLC (RPLC) is ineffective in for only a few separation types. HPLC is applied for molecular weight determination, in analytical chemistry, pharmaceutical and drug science, clinical sciences, food technology, and consumer products, combinatorial chemistry, polymer chemistry, environmental chemistry and green chemistry.

Related Societies:

Track 9:- Chromatography in Bio-Medical Research

HPLC is the most versatile of all chromatography methods but also the most complex. It was first made available in the laboratory during the 1970s and is currently used for the analysis of amino acids, peptides, proteins, carbohydrates, lipids, nucleic acids and related compounds, vitamins, hormones, metabolites, and drugs. HPLC can be coupled to various detectors such as UV, fluorescence or mass spectrometry (LC/MS and LC/MS/MS) and is routinely used for quantitative analysis in biological samples such as blood, urine and other body fluids. HPLC consists of using a liquid mobile phase to pass under high pressure a mixture of analytes extracted from the sample through a column containing the stationary phase. Analyte separation is based on differences in interaction with both the mobile phase and the stationary phase.

HPLC is a proven method for isolating analytes of interest in complex matrices such as biological fluids. Its use in the clinical laboratory has steadily increased over the past decades as its unmatched analytical performance and versatility allows for testing of many different types of clinically relevant analytes. With the recent advances in detection technology such as mass spectrometry and sample preparation techniques such as bio-affinity chromatography and online automation, HPLC based methods will likely remain the gold standard of clinical testing for many of the current but also future biomarkers and therapeutic drugs.

Related Societies:

Track 10:- Hyphenated Chromatography Methods

The hyphenated technique is developed from the coupling of a separation technique and an on-line spectroscopic detection technology. Several remarkable improvements in hyphenated analytical methods over the last two decades have significantly broadened their applications in the analysis of biomaterials, especially natural products, pre-isolation analyses of crude extracts or fraction from various natural sources, isolation and detection of natural products, chemical fingerprinting, testing of herbal products, de-replication of natural products, and metabolomics. Rapid identification and characterization of known and new natural products directly from plant and marine sources without the necessity of isolation and purification can be achieved by various modern hyphenated techniques. Techniques like HPLC coupled to NMR (Nuclear Magnetic Resonance) or electrospray ionization tandem mass spectrometry (ESI-MS-MS) have been proven to be extremely powerful tools in natural product analysis, as they aid in the fast screening of crude natural product extracts or fractions for detailed information about metabolic profiles, with minimum quantity of material. Hyphenated HPLC techniques include HPLC-MS, HPLC-ESI-MS, HPLC-IC-MS, HPLC-NMR-MS, HPLC-DAD, HPLC-CE-MS, HPLC-UV, Coupling LC and MALDI-TOF.

Related Societies:

Track 11:- Chromatography as Separation Techniques

High Performance Liquid Chromatography (HPLC) is a non-destructive procedure for resolving a complex mixture into its individual fractions or compounds. It is based on differential migration of solutes with the solvents. The solutes in a mobile phase go through a stationary phase. Those solutes with a high affinity for the mobile phase will spend more time in this phase than the solutes that prefer the stationary phase. As the solute rise up through the stationary phase they separate. The process is called chromatographic development. The fraction with greater affinity to stationary layer travels slower and shorter distance while that with less affinity travels faster and longer.

In normal-phase chromatography, the stationary phase is polar and the mobile phase is nonpolar. In reversed phase the stationary phase is nonpolar and the mobile phase is polar.

Flash Column Chromatography (FCC) or Flash Chromatography is a quickest and the easiest way to separate complex mixtures of compounds. It uses compressed air to push the solvent through the column. This provides better separation and reduces the amount of time required to run a column.

Ion exchange chromatography (IEC) uses an ion exchange mechanism to separate analytes based charge difference. It is performed in columns but can also be useful in planar mode. It uses a charged stationary phase to separate compounds including cations, anions, amino acids, proteins, lipids and peptides. Loading samples in buffers of low ionic strength makes ion exchange chromatography an excellent purification step after HIC.

Affinity chromatography is based on selective non-covalent interaction between an analyte and sample molecules. It is highly specific, but not robust method. It is used in biochemistry in the purification of proteins bound to tags. Fusion proteins are labelled with compounds such as antigens or biotin which bind to the stationary phase specifically. Later after purification, some of these tags are removed and the pure protein is obtained. Immobilized Metal Affinity Chromatography is used to separate molecules based on the relative affinity for the metal. Often these columns can be loaded with different metals to create a column with a targeted affinity.

Chiral chromatography includes the separation of stereoisomers. Enantiomers have no chemical or physical differences apart from being three-dimensional mirror images. For chiral separations to happen, either the mobile phase or the stationary phase must themselves be made chiral by inducing different affinities between the analytes.

Size-exclusion chromatography (SEC) also known as gel filtration chromatography, separates molecules according to the size or more accurately according to the hydrodynamic diameter or the hydrodynamic volume. Small molecules enter the pores of the media where they are trapped and removed from the flow of the mobile phase. Mean residence time in the pores depends upon the effective size of the analyte molecules. It is a low-resolution chromatography technique and thus it is used for determining the tertiary structure and quaternary structure of purified proteins.

Related Societies:

Track 12:- High Efficiency & High Resolution Techniques

UHPLC (Ultra-HPLC) or UPLC (Ultra Performance Liquid Chromatography) is now being adopted in industrial labs, especially the pharmaceutical industry due to its high speed, high resolution and solvent saving. A UHPLC method uses a sub-2micron column as it reduces the analysis time by 80% and save the mobile phase consumption by a huge amount compared to the conventional HPLC. In addition, the much shorter run time significantly reduces UHPLC method development scouting time. HPLC method development principles can be applied to UHPLC method development. Micro and Nano HPLC ensure high levels of flow rate flexibility and reproducibility.

Hydrophilic interaction chromatography or hydrophilic interaction liquid chromatography (HILIC) is a variant of normal phase liquid chromatography that partly overlaps with other chromatographic applications such as ion chromatography and reversed phase liquid chromatography. It uses hydrophilic stationary phases with reversed-phase type eluents.

Related Societies:

Track 13:- Method Development & Validation

Quality can be designed to processes through systematic implementation of an optimization strategy to establish a thorough understanding of the response of the system quality to given variables, and the use of control strategies to ensure quality. The concept of method development includes modelling of the influence of values of variables on quality, design of experiments, and simplification of processes as information is collected. The extension of QbD (Quality by Design) philosophies is now applied to the development of manufacturing processes and analytical methods. The ability of a chromatographic method to successfully separate, identify and quantitate species is determined by a powerful factor called experimental design. Automation of a process is one of the keys for increasing the productivity of a research group.

Related Societies:

Track 14:- Recent Advances in Chromatography

The HPLC methodology applied to the analysis of biological samples makes it possible for the identification of many metabolites. Samples from two human embryos culture medium were analysed by high-pressure liquid chromatography–mass spectrometry (HPLC–MS). They work on the principle that many microorganisms have their own unique mass spectral signature based on the particular proteins and peptides that are present in the cells. Identification of unknown peaks in gas chromatography (GC-MS)-based discovery metabolomics is challenging, and remains necessary to permit discovery of novel or unexpected metabolites that may allergic diseases processes and/or further our understanding of how genotypes relate to phenotypes. Here, we introduce two new technologies and advances in pharmaceutical analytical methods that can facilitate the identification of unknown peaks.

Related Societies:

Track 15:- Chip Based Chromatography Separations

This includes a micro fabricated separation device. The availability of the fused-silica capillary marked a significant breakthrough for gas chromatography and all gas chromatographs manufactured were equipped to use fused silica capillary columns. Fused-silica capillaries have a huge contribution to the developments of other micro separation technologies like supercritical fluid chromatography. The success of one separation technique relies on sample introduction technologies, separation column and sensitive detectors that can preserve chromatographic fidelity of high resolution chromatographic peaks, as is evident from the many injectors and detectors optimized and available for open tubular GC. A particle packed column is comprised of a Nano litre enrichment column and a micron or sub-micron separation column packed with suitable grade of C18. The HPLC-Chip is made from a biocompatible polyimide and the functionality of this chip is equivalent to conventional Nano spray LC/MS. Monoliths consist of a single rod of porous material with several unique features in terms of permeability and efficiency. Micro-fabricated column based on pillar-arrays were formed by arrays of nonporous silicon pillars with a diameter of approximately 4.3μm. The pillars were covalently coated with a monolayer of hydrophobic C8-chains to enable reversed-phase LC separations.

Related Societies:

Track 16:- Market Growth of Chromatography

The global chromatography instrumentation market is segmented on the basis of systems, consumables, applications, and regions. The report studies the global chromatography instruments market for the forecast period of 2015 to 2020. The market is expected to reach USD 9.223 Billion by 2020 from USD 7.062 Billion in 2015, at a CAGR of 5.5%.

It is anticipated that North America and Europe will continue to lead the market over the next five years; the chromatography market in Asia will expand and increase its market share. The drivers behind the expansion are two-fold: first the expansion of local companies in Asia and secondly, Western Pharma outsourcing its research and manufacturing operations to Asia, particularly China and India.

Related Societies:

Chromatography is used extensively in all areas of chemical analysis from typical biological compounds to those in polluted environment. The technique is extensively used by the pharmaceutical industry for both research purposes and for quality control. Similarly, the biochemical and biotechnology industries widely use chromatographic techniques and in many cases alternative methods are not available. Since its invention, chromatography has become a key tool for separation, identification, purification and quantification of several compounds. Chromatography is under constant development owing to the growing research needs in academic and industrial levels. This has led to the combination of HPLC with other spectroscopic techniques like NMR, MS, GC, IC, SE and MALDI. Hyphenated HPLC techniques are now more investigated and used to combine the efficiency of more than one technique.

High Performance Liquid Chromatography (HPLC) is the most popular analytical technique for a wide variety of samples from typical biological compounds to those in polluted environment. HPLC is unique because of its features like pressure stable column, constant and high linear velocity of mobile phase and most important densely packed column with reduced particle size, less than 10µm (less than 2µm in UHPLC) .

Advanced Chromatography 2019 is an international platform for presenting research about separation techniques and related fields thus contributes to the dissemination of knowledge for the benefit of both the academia and business. This event brings together the top professionals in the field along with the highly affiliated professors to explore the advancements and latest applications achieved in the field of chromatography. Advanced Chromatography 2019 discusses various fields of analytical chemistry employed in theoretical, organic, inorganic, pharmaceutical and life science fields which mark the support for the advanced and much needed research by their study on various topics. The scientific program will focus on current advances in the research and use of chromatography and related with particular focus on its roles and applications in various fields.

Market Summary:

The enormous market of chromatography instrumentation includes chromatography systems like TLC, HPLC, UPLC etc. and chromatography consumables like filters, columns, solvents etc. The international life science and chemical instrumentation market is expected to increase at CAGR of 6.9% reaching $48.84 billion by 2019. Increasing government investments in pharmaceutical R&D in emerging nations, technological advancements in the analytical instruments, growing food safety concerns, increasing life science research and development expenditure, and progressing drug discovery and clinical diagnostics field are the key factors driving the growth of life science and chemical instrumentation market. Additionally, the key factors offering new growth opportunities for the market players include rising environmental safety concerns, growing proteomics market and increasing demand of analytical instruments from applied markets. The Europe Liquid Chromatography Reagents market is determined to grow at a CAGR of 9.9% from 2014 to 2019. The market growth is stimulated by extensive use of chromatographic techniques in every minute analysis.

Why to attend Chromatography-HPLC Congress 2018?

Advanced Chromatography 2019 will provide an opportunity and platform to detail the research works of analytical expertise from various scientific backgrounds and the same can be perceived by young researchers and students. The conference mainly aims to promulgate knowledge on chromatography and unveil the advances in Chromatography techniques. Both life sciences and chemical sciences need analytical techniques in course of research work and therefore Advanced Chromatography 2019 would be a perfect venue to share and develop knowledge on key analytical tools.

Advanced Chromatography 2019 will congregate renowned speakers, industrial experts and researchers from both academia and Pharmaceutical industry will join together to discuss their views and research. The conference will be comprised of sessions by world class experts in the field of chromatography and separation technology. In Advanced Chromatography-2019, international symposiums, B2B meetings, international workshops will also be organized to discuss the specific topics in the field of Chromatography and Chemistry.

A Unique Opportunity for Advertisers and Sponsors at this International event.

Global Chromatography and HPLC Associations

American Chemical Society
American Organization of Analytical Chemists International (AOAC)
American Society for Mass Spectrometry
An International Separation Science Society
Association of Analytical Communities (AOAC) International
Association of Separation Scientists and Technologists
Australian and New Zealand Society for Mass Spectrometry
Austrian Society for Analytical Chemistry
California Separation Science Society (CaSSS)
Canadian Society for Analytical Sciences
Chinese American Chromatography Association (CACA)
Chromatographic Society of India (CSI)
Cooperation on International Traceability in Analytical Chemistry (CITAC)
International Council of Chemical Associations
Mendeleev Russian Chemical Society
Royal Australian Chemical Institute
Royal Society of Chemistry
Society for Applied Spectroscopy
Society for Chromatographic Sciences (SCS, Japan)
South African Chromatography Society (ChromSA)
The International Association for the Advancement of High Performance Thin Layer Chromatography (HPTLC Association)
The Japan Society for Analytical Chemistry (JSAC)

Major Associations in Europe

British Mass Spectroscopic Society
ChromSoc-The Chromatographic Society
Czech Chemical Society
European Association for Chemical and Molecular Sciences (EuCheMS)
European Federation for Pharmaceutical Sciences
European Society for Separation Science
Italian Chemical Society
Royal Netherlands Chemical Society
Swedish Mass Spectrometry Society
The Israeli Society for Mass Spectrometry – ISMS

Conference Highlights

To share your views and research, please click here to register for the Conference.

To Collaborate Scientific Professionals around the World

Conference Date	April 22-24, 2019
Sponsors & Exhibitors	~~Click here for Sponsorship Opportunities~~
Speaker Opportunity Closed	Day 1	Day 2
Poster Opportunity Closed	Click Here to View

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All accepted abstracts will be published in respective Our International Journals.

Abstracts will be provided with Digital Object Identifier by

11^th International Conference & Expo on Chromatography Techniques April 22-24, 2019 Dublin, Ireland

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Advanced Chromatography 2019

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To Collaborate Scientific Professionals around the World

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