Imre Molnár
Molnár-Institute for Applied Chromatography, Germany
Title: Modeling UHPLC separations
Biography
Biography: Imre Molnár
Abstract
HPLC methods dominantly control the quality of many chemical and pharmaceutical products and are used in the research and development in the field of Life Sciences (food analysis, clinical studies and regulatory submissions). For the last 40 years, the usual way of HPLC method development was done by trial and error method, but regulatory agencies are requesting for the new Analytical Quality by Design (AQbD) paradigm, i.e., a systematic development of methods. One way of doing this is using modeling tools, which allow reducing the time for development and supports a better communication between different groups in a global world. The lecture will address the most important aspects of modern UHPLC modeling on the basis of several case studies.