Bogusław Buszewski
Nicolaus Copernicus University, Poland
Title: New stationary phases for separation of biologically active compounds: Synthesis, characterization and application
Biography
Biography: Bogusław Buszewski
Abstract
The need for selectivity determines the synthesis and development of chemically bonded stationary phases that contain various functional groups. Functional groups with specific properties, together with appropriate mobile phase qualitative and quantitative composition allow controlling separation selectivity. Silica gel and organic polymers are the most often used support for stationary phases. During preparation of the packing, organic ligands can be easily bonded to silica support which has good mechanical stability that supports efficiency of chromatographic separations. Presented study deal with the synthesis of novel group of chromatographic materials that contain different polar functional group incorporated to alkyl chains. Detailed instrumental characterization of the surface is also presented, including elemental analysis, spectroscopic techniques and chromatographic study. Solvation properties of novel materials as well as creation of electric double layer on its surface give also interesting information about surface properties. The main part of the presented work will focus of chromatographic applications of novel chromatographic materials in separation of various groups of biologically active compounds.